Model DetailsBone osteosarcoma

Model Name

Bone osteosarcoma

Strain

B6.129-Trp53tm1Tyj/+ Xpatm1Hvs

Tumor Inducing Agent(s)

Hormone : diethylstilbestrol (DES)

Tumor Synonym

osteosarcoma

Strain Synonyms

Xpa/p53  •  C57BL/6 Xpa/p53  •  combined Xpa homozygous and p53 heterozygous knockout
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Bone Male

33%

(5 of 15 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McAnulty PA, Toxicol Pathol 2005;33(5):609-20
Liver Male

80%

(4 of 5 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
McAnulty PA, Toxicol Pathol 2005;33(5):609-20
Spleen Male

20%

(1 of 5 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McAnulty PA, Toxicol Pathol 2005;33(5):609-20
Bone Female

13%

(2 of 15 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McAnulty PA, Toxicol Pathol 2005;33(5):609-20
Spleen Female

50%

(1 of 2 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McAnulty PA, Toxicol Pathol 2005;33(5):609-20