STUDY SUMMARY
Skin Cancer Model: TM00339
NSG™ mice engrafted with passage 5 tumors for model TM00339
were randomly assigned to one of these treatment groups:
- 0.5% carboxymethyl cellulose (CMC) (10 ml/kg; PO daily for 21 days; N=10)
- Cisplatin (2 mg/kg; IV once per week for three times; N=10)
- Dabrafenib (100 mg/kg; PO daily for 21 days; N=10)
- Temozolomide (30 mg/kg; PO daily for 21 days; N=10)
Mice were monitored for tumor volume at least twice per week throughout the study period.
• Treatment groups
• Individual subjects / spider plot
• RECIST scores
• Waterfall plot
• TGI plot
• Protocols
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