STUDY SUMMARY
Breast (ER+) Cancer Model: TM00386
NSG™ mice engrafted with passage 6 tumors for model TM00386
were randomly assigned to one of these treatment groups:
- 5% dextrose in water (vehicle control; 5 ml/kg; IV once per week for three times; N=8-10)
- Cisplatin (2 mg/kg; IV once per week for three times; N=8-10)
- Cyclophosphamide (40 mg/kg; IV once per week for three times; N=8-10)
- Docetaxel (10 mg/kg; IV once per week for three times; N=8-10)
- Doxorubicin (2 mg/kg; IV once per week for three times; N=8-10)
- Tamoxifen (10 mg/kg; PO once daily for 21 days; N=8-10)
Mice were monitored for tumor volume at least twice per week throughout the study period.
• Treatment groups
• Individual subjects / spider plot
• RECIST scores
• Waterfall plot
• TGI plot
• Protocols
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