Pathology Image Detail

Caption

Haired skin - Normal tissue: There is mild labeling of eosinophils in the dermis (tissue fixed in Fekete's solution, heat-mediated antigen retrieval in citrate buffer, pH=6.0, 1:150 dilution). There is moderate background in the connective tissue, skeletal muscles, and hair follicles. There is also strong non-specific labeling macrophages due to the persistance of endogenous peroxidase activity. Other antibodies allow more appropriate detection of eosinophils in paraffin-embedded tissues.

Description

Haired skin - Normal tissue. Eosinophil peroxidase immunohistochemistry

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for eosinophil peroxidase
Image Probes

Type: antibody

Name
anti-eosinophil peroxidase (MAB1087)
Target
human eosinophil peroxidase
Supplier
Chemicon
Notes
Clone: AHE-1; mouse anti-human IgG1 monoclonal antibody

Model

MMHC ID
MTB:27695
Tumor Name
Skin • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
haired skin, normal tissue
Organ Affected
Skin
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/Ka-Sharpincpdm
Strain Types
spontaneous mutation
General Note
Homozygous mice.
Strain Synonyms
C57BL/Ka (cpdm/cpdm)
C57BL/Ka-cpdm
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown