Pathology Image Detail

Caption

Mammary gland: this is a nodular, densely cellular, expensile neoplastic mammary mass which is surrounded by a thin fibrous capsule. This neoplasm is made of trabeculae and solid areas supported by a small amount of fibrovascular stroma. Areas of cavitation are present at the center of the neoplasm. This type of tumor is typical of FVB/N mice transgenic for neu. As exemplified in this case, central cavitation is common in the largest tumors.

Description

Mammary gland, adenocarcinoma, trabecular to solid, with pulmonary emboli to the lungs

Age at Necropsy

206 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25575
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary gland, adenocarcinoma, trabecular to solid, with pulmonary emboli to the lungs
Organ Affected
Lung
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(MMTVneu)202Mul/J
Strain Types
transgenic
General Note
Homozygous mice
Strain Synonyms
FVB/N-TgN(MMTVneu)202Mul
MMTV neu
FVBN202
FVBN202 neu
MMTV-erbB2
FVB-Neu
MMTV-Neu
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
206 days