Caption |
Colonic adenoma: this high power photomicrograph illustrates the difference between the normal epithelium (lower left corner of the photomicrograph) and the neoplastic epithelium. Neoplastic cells are columnar. They have a more basophilic cytoplasm compared to non-neoplastic cells and never contain a mucus vacuole. Their nucleus is bigger and with a more clumped chromatin than neoplastic cells. Mitotic rate is elevated. A few degenerated neoplastic cells are in the lumen of some neoplastic glands. |