Pathology Image Detail

Caption

Small intestine: a small pedunculated mass is arising from the intestinal epithelium. This mass is composed of contoured and anastomosed glands supported by a small amount of fibrovascular stroma. The glands are lined by a one cell-thick columnar epithelium where neoplastic cells occasionally pile-up up to 3 cells-thick. There are numerous mitoses. Neoplastic cells have a moderate amount of amphophilic cytoplasm. There is no evidence of invasion in the submucosa.

Description

Adenoma, small intestine

Age at Necropsy

84 days

Contributor

Kemp CJ (J:97126)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25616
Tumor Name
Intestine - Small Intestine • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
small intestine adenoma
Organ Affected
Intestine - Small Intestine
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6-ApcMin/+
Strain Types
chemically induced mutation
General Note
Heterozygous mice. These mice are the product of an intercross between strains on a predominantly C57BL/6 background.
Strain Synonyms
Min/+ p27+/+
B6.Cg-ApcMin/+
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
84 days