Pathology Image Detail

Caption

Intestinal adenoma: this high power photomicrograph illustrates portions of the neoplasm where neoplastic cells pie-up disorderly (upper left portions of the photomicrograph) and other areas where neoplastic cells are columnar and form a one cell-thick epithelium. Neoplastic cells have indistinct cell borders and a moderate amount of amphophilic cytoplasm. The nucleus is oval, oriented in the long axis of the cell, hypochromatic, with a clumped chromatin and 1-2 small basophilic nucleoli. Mitoses are present. A few globule leukocytes (arrowheads) are present in the solid portions of the neoplasm.

Description

Adenoma, small intestine

Age at Necropsy

84 days

Contributor

Kemp CJ (J:97126)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25616
Tumor Name
Intestine - Small Intestine • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
small intestine adenoma
Organ Affected
Intestine - Small Intestine
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6-ApcMin/+
Strain Types
chemically induced mutation
General Note
Heterozygous mice. These mice are the product of an intercross between strains on a predominantly C57BL/6 background.
Strain Synonyms
Min/+ p27+/+
B6.Cg-ApcMin/+
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
84 days