Pathology Image Detail

Caption

 Haired skin: neoplastic cells are large, histiocytoid, with ill-defined cell borders and a moderate amount of amorphous acidophilic cytoplasm. They have 1-25 nuclei. Nuclei are oval, medium-sized, often eccentric, and normochromatic to hypochromatic. Anisokaryosis is mild. Anisocytosis is marked. Mitoses are not detected in this photomicrograph. The tumor is diffusely infiltrated by a small number of lymphocytes and granulocytes.

Description

 Malignant histiocytosis, haired skin (lip)

Age at Necropsy

 259 days

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:25958
Tumor Name
Leukocyte - Monocyte - Macrophage - Histiocyte • lymphoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Malignant histiocytosis, haired skin (lip)
Organ Affected
Skin
Frequency
observed
Reference
J:94320

Strain
Strain
SJL/J
Strain Types
inbred
Strain Synonyms
SJL
Swiss Jim Lambert
SJL/J, H-2s
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
259 days