Pathology Image Detail

Caption

Haired skin: neoplastic trabeculae and nests comprise a basal layer of cells, 3-10 layers of cells resembling the cells of the stratum spinosum, and a variably thick layer of cells resembling the cells of the stratum granulosum. Most neoplastic structures are moderately distended by cornified material.

Description

Squamous cell carcinoma, well-differentiated, haired skin

Age at Necropsy

156 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:26089
Tumor Name
Skin • squamous cell carcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
squamous cell carcinoma, well-differentiated, haired skin
Organ Affected
Skin
Frequency
observed
Reference
J:94320

Strain

Strain
B6.129P2-Apoa1tm1Unc/J
Strain Types
congenic
targeted mutation (knockout)
General Note
Homozygous mice. Backcrossed to C57BL/6J.
Strain Synonyms
Apoa1 -/-
B6.129P2-Apoa1tm1Unc
C57BL/6J-Apoa1tm1Unc
Apo A1-
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
156 days