Pathology Image Detail

Caption	Paravertebral skeletal muscles: the neoplasm is composed of closely packed whirling and streaming bundles supported by a moderate amount of fibrovascular stroma. This photomicrograph illustrates the most common phenotype of neoplastic cells in this neoplasm. Neoplastic cells are small to medium-sized, fusiform to oat-shaped, with ill-defined cell borders and a small amount of fibrillar acidophilic cytoplasm.
Description	Rhabdomyosarcoma, poorly differentiated, skeletal muscles
Age at Necropsy	221 days
Contributor	Mikaelian I (J:94320)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Name: Muscle - Striated - Skeletal • rhabdomyosarcoma - poorly differentiated

General Note: Heterozygous mice. The genetic background of these mice is congenic C57BL/6J.

Strain Synonyms: B6.129S2-Trp53^tm1Tyj; C57BL/6J-Trp53^tm1Tyj; p53+/-; p53 heterozygous (+/-); C57BL/6J-Trp53^tm1Tyj; p53(+/-); B6.129S2-Trp53^tm1Tyj; p53+/-; p53^+/-