Pathology Image Detail

Caption

 Undifferentiated sarcoma: a few granulocytes undergo emperipolesis through the cytoplasm of a neoplastic cell (arrowhead). A few adipocytes (*) are entrapped in the neoplasm. There is massive diffuse infiltration of the neoplasm by granulocytes.

Description

 Sarcoma, undifferentiated, subcutis

Age at Necropsy

 147 days

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:26699
Tumor Name
Mesodermal cell/mesoblast • sarcoma - undifferentiated
Treatment Type
None (spontaneous)
Tumor Synonyms
sarcoma, undifferentiated, subcutis
Organ Affected
Subcutis
Frequency
observed
Reference
J:94320

Strain
Strain
B6.129S2-Trp53tm1Tyj/J
Strain Types
congenic
targeted mutation (knockout)
General Note
Heterozygous mice. The genetic background of these mice is congenic C57BL/6J.
Strain Synonyms
B6.129S2-Trp53tm1Tyj
C57BL/6J-Trp53tm1Tyj
p53+/-
p53 heterozygous (+/-)
C57BL/6J-Trp53tm1Tyj
p53(+/-)
B6.129S2-Trp53tm1Tyj
p53+/-
p53+/-
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
147 days