Pathology Image Detail

Caption

 Kidney: the interstitium of the kidney is moderately expanded by closely-packed sheets of neoplastic lymphocytes. Neoplastic cells are small, round, with distinct cell borders and a small amount of pale basophilic cytoplasm. Their nucleus is central, small to medium-size, round, and hyperchromatic.

Description

 Lymphoma, lymphocytic, kidney

Age at Necropsy

 147 days

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:26703
Tumor Name
Leukocyte - Lymphocyte • lymphoma - lymphocytic
Treatment Type
None (spontaneous)
Tumor Synonyms
lymphocytic lymphoma
Organ Affected
Kidney
Frequency
observed
Reference
J:94320

Strain
Strain
BKS.Cg-Dock7m +/+ Leprdb/J
Strain Types
congenic
spontaneous mutation
General Note
Heterozygous mice - "misty" mutation; Heterozygous mice - "diabetes" mutation; These 2 mutations are closely linked and are maintained in repulsion in this strain from The Jackson Laboratory.
Strain Synonyms
BKS.Cg-m +/+ Leprdb/J
BKS.Cg-m +/+ Leprdb
C57BLKS/J-m +/+Leprdb
BKS db
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
147 days