Pathology Image Detail

Caption

 Lymph node: cortixal and medullary areas of the kidney are markedly expanded by densely-packed monotonous sheets of neoplastic lymphocytes. The overall architecture of the lymph node is retained. Subcortical, interfollicular, and medullary sinuses are packed with macrophages.

Description

 Lymphoma, lymphocytic, lymph node

Age at Necropsy

 147 days

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:26702
Tumor Name
Leukocyte - Lymphocyte • lymphoma - lymphocytic
Treatment Type
None (spontaneous)
Tumor Synonyms
lymphocytic lymphoma
Organ Affected
Lymph node
Frequency
observed
Reference
J:94320

Strain
Strain
BKS.Cg-Dock7m +/+ Leprdb/J
Strain Types
congenic
spontaneous mutation
General Note
Heterozygous mice - "misty" mutation; Heterozygous mice - "diabetes" mutation; These 2 mutations are closely linked and are maintained in repulsion in this strain from The Jackson Laboratory.
Strain Synonyms
BKS.Cg-m +/+ Leprdb/J
BKS.Cg-m +/+ Leprdb
C57BLKS/J-m +/+Leprdb
BKS db
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
147 days