Pathology Image Detail

Caption

 The thymus has been entirely replaced and markedly expanded by a densely cellular neoplasm composed of closely packed sheets of round cells. The heart (H) is present on this section.

Description

 Lymphoma, thymic

Age at Necropsy

 107 days

Contributor

 Sundberg J (J:94307)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:26704
Tumor Name
Leukocyte - Lymphocyte • lymphoma
Treatment Type
None (spontaneous)
Tumor Synonyms
thymic lymphoma
Organ Affected
Thymus
Frequency
observed
Reference
J:94320

Strain
Strain
C3Ou.129S2(B6)-Trp53tm1Tyj/J
Strain Types
congenic
targeted mutation (knockout)
General Note
Heterozygous mice. Mice carrying this mutation on a mixed 129S2 x C57BL/6 genetic background were backcrossed at least 5 times to C3H/HeOuJ.
Strain Synonyms
C3Ou.129S2(B6)-Trp53tm1Tyj
C3H/HeOuJ-Trp53tm1Tyj
C3Ou.129S2-Trp53tm1Tyj/J
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
107 days