Pathology Image Detail

Caption

Monstrocellular glioma: the neoplasm is composed of solid sheaths supported by a small amount of fibrovascular stroma. Most neoplastic cells a medium-size, histiocytoid, with indistinct cell borders and a moderate amount of acidophilic cytoplasm. The nucleus is central, large, medium-size, hypochromatic, with a clumped chromatin and 1-3 medium-size to large nucleoli. A few nuclei are large and multilobulated; their chromatin often is lacy. Anisokaryosis and anisocytosis are prominent. Mitoses are numerous.

Description

Monstrocellular glioma, spinal cord

Age at Necropsy

unknown

Contributor

Fancher K (J:97128)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:26705
Tumor Name
CNS - Spinal cord • glioblastoma - giant cell
Treatment Type
None (spontaneous)
Tumor Synonyms
monstrocellular glioma, spinal cord
Organ Affected
CNS - Spinal cord
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6J-Tg(WapTAg)1Knw/J
Strain Types
transgenic
Strain Synonyms
C57BL/6J-Tg(WapTAg)1Knw
WapTag 1
WAPTag 1
C57BL/6J WAPTag 1
WAP-SV40 Tag
WAPTag
C57BL/6J-TgN(WapTAg)1Knw
C57BL6/J-Tag
WAPT1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown