Pathology Image Detail

Caption

 Mammary adenocarcinoma with epithelial to mesenchymal transition, immunohistochemistry for keratin 17: there is strong cytoplasmic labeling of most spindloid cells for keratin 17. Expression of keratin 17 appears to be synchronous with epithelial to mesenchymal transition.

Description

 Adenocarcinoma with epithelial to mesenchymal transition, immunohistochemistry for keratin 17, mammary gland

Age at Necropsy

 unknown

Contributor

 Fancher K (J:97128)

Pathologist

 Mikaelian I (J:94320)

Method

 IHC for keratin 17
Image Probes

Type: antibody
Name
anti-keratin 17
Target
mouse and human keratin 17 (recombinant, C terminal)
Notes
polyclonal rabbit anti-mouse keratin 17 antibody (kind gift of Dr. Pierre Coulombe, Johns Hopkins University School of Medicine)

Model
MMHC ID
MTB:26706
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
adenocarcinoma with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
C57BL/6J-Tg(WapTAg)1Knw/J
Strain Types
transgenic
Strain Synonyms
C57BL/6J-Tg(WapTAg)1Knw
WapTag 1
WAPTag 1
C57BL/6J WAPTag 1
WAP-SV40 Tag
WAPTag
C57BL/6J-TgN(WapTAg)1Knw
C57BL6/J-Tag
WAPT1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown