Pathology Image Detail

Caption

Mammary gland: this is a nodular, encapsulated, well-delineated, densely cellular, expansile neoplastic mammary neoplasm, the margins of which are present on the section. The neoplasm is composed of closely-packed glands, a few solid areas, and a few papillary areas lined by a 1-3 cells thick epithelium supported by a small amount of fibrovascular stroma. Large areas of coagulation necrosis (*) are scattered throughout of the tumor (comedo pattern).
NOTE: Adjacent mammary ducts and acini are packed with cells which are histologically indistinguishable from the neoplastic cells of the main mass (in situ mammary adenocarcinoma).

Description

Adenocarcinoma, glandular, comedo, papillary, mammary gland

Age at Necropsy

unknown

Contributor

Fancher K (J:97128)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:26707
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
adenocarcinoma, glandular, comedo, papillary, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6J-Tg(WapTAg)3Knw/J
Strain Types
transgenic
Strain Synonyms
C57BL/6J-Tg(WapTAg)3Knw
C57BL/6J-Tg(WAPTAg)3Knw/J
C57BL/6J-TgN(WAPTAg)3Knw
C57BL/6J-TgN(WapTAg)3Knw
C57BL/6J WAPTag 3
WAPTag
WAP-SV40 Tag
WAPTag 3
WAPTag3
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown