Pathology Image Detail

Caption

Mammary gland: the mammary gland is effaced by a nodular, multilobular, partly encapsulated, invasive, densely cellular neoplasm which is associated with emboli (*) in nearby veins. Large areas of liquefactive necrosis are present at the center of the neoplasm. Neoplastic lobules are separated by a small amount of fibrovascular stroma, and are composed of solid areas and a few glands lined by a one cell-thick epithelium. Neoplastic small to medium-sized, cells are polygonal to cuboidal, with indistinct cell borders, and with a small to moderate amount of acidophilic cytoplasm.

Description

Adenocarcinoma, solid, glandular, comedo, mammary gland

Age at Necropsy

unknown

Contributor

Fancher K (J:97128)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:26711
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
adenocarcinoma, solid, glandular, comedo, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6J-Tg(WapTAg)3Knw/J
Strain Types
transgenic
Strain Synonyms
C57BL/6J-Tg(WapTAg)3Knw
C57BL/6J-Tg(WAPTAg)3Knw/J
C57BL/6J-TgN(WAPTAg)3Knw
C57BL/6J-TgN(WapTAg)3Knw
C57BL/6J WAPTag 3
WAPTag
WAP-SV40 Tag
WAPTag 3
WAPTag3
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown