Caption |
Circumscribed adenocarcinoma: the mammary parenchyma is effaced by a nodular, expensile, unencapsulated, densely cellular, polycystic mass. This mass is composed of glands that show various degrees of ectasia, contain an amorphous acidophilic material, and are lined by a one cell-thick cuboidal to columnar epithelium supported by a scant amount of fibrovascular stroma. Neoplastic cells multifocally pile-up in a disorderly fashion. Neoplastic cells are polygonal to columnar, with indistinct cell borders and a moderate to large amount of strongly amphophilic cytoplasm. The nucleus is central, round to oval, hypochromatic, and with a large basophilic nucleolus. Mitoses are numerous. |