Caption |
Mammary adenocarcinoma: the neoplasm is composed, in this area, of closely-packed papillae supported by a small amount of fibrovascular stroma. Neoplastic structures are lined by a one cell-thick cuboidal to columnar epithelium. Neoplastic cells have distinct cell borders and a moderate amount of strongly amphophilic cytoplasm that occasionally contains small lipid vacuoles. The nucleus is large, central, oval, hyperchromatic, and with a coarsely-clumped chromatin. Numerous neoplastic cells undergo single cell necrosis and mitotic rate is elevated. Macrophages with a foamy cytoplasm are present in between neoplastic papillae. |