Pathology Image Detail

Caption

Mammary gland: the cellular area in this carcinoma in situ is characterized by epithelial cells piling-up and forming small papillae in a structure that resembles an intralobular duct. This change is associated with mild to moderate interstitial fibrosis and lymphoplasmacytic inflammation. Most neoplastic cells contain lipid vacuoles which are larger and more numerous in the cells lining the dysplastic acini surrounding the most advanced lesions.

Description

Carcinoma in situ, papillary, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29172
Tumor Name
Mammary gland • carcinoma in situ
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma in situ, papillary, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(Rr28-Igf2)1bDdp
Strain Types
transgenic
General Note
Hemizygous mice.
Strain Synonyms
FVB/N-Tg(H19-Igf2)1BDdp
pmH19eIgfMlu 1B
1B
FVB/N-Tg(Igf2)1bDdp
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown