Pathology Image Detail

Caption

Papillary and secretory mammary adenocarcinoma: the neoplasm is composed of glands and papillae lined by a one cell-thick cuboidal to low columnar epithelium and supported by a small to moderate amount of collagen-rich fibrovascular stroma. Neoplastic cells are cuboidal to low columnar, with indistinct cell borders and a moderate amount of strongly amphophilic cytoplasm that occasionally contains a few small vacuoles of lipids. The nucleus is basal to central, medium-sized, oval, and normochromatic. The luminal spaces are filled with degenerated neoplastic cells. The stroma is infiltrated by a moderate number of neutrophils, lymphocytes and plasma cells.

Description

Adenocarcinoma, papillary, secretory, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29175
Tumor Name
Mammary gland • adenocarcinoma - papillary
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, papillary, secretory, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(Rr28-Igf2)2Ddp
Strain Types
transgenic
General Note
Hemizygous mice.
Strain Synonyms
FVB/N-Tg(Igf2)2Ddp
FVB/N-Tg(H19-Igf2)2Ddp
2
umH19eIgfMlu
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown