Pathology Image Detail

Caption

Mammary gland: the mammary gland is expanded by a large polycystic mass lined by a one to two cells-thick cuboidal to tall columnar epithelium. The cells lining the cysts have distinct cell borders and a moderate to large amount of acidophilic cytoplasm that often contain lipid vacuoles of various sizes. The nucleus is randomly located in the cell, is large, oval, hyperchromatic, and with a coarsely clumped chromatin. Anisokaryosis and anisocytosis are prominent. A few mitoses are detected.

Description

Mammary gland - Macrocyst, with atypia

Age at Necropsy

300 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29177
Tumor Name
Mammary gland • cyst - macrocyst
Treatment Type
None (spontaneous)
Tumor Synonyms
Mammary gland - Macrocyst, with atypia
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(Trp53R172H)8512Jmr Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps(Trp53R172H)8512Jmr
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
300 days