Pathology Image Detail

Caption

Mammary gland: mammary lobules are prominent, are filled with an often inspissated proteinaceous fluid, and are lined by a prominent epithelium. Luminal cells of all alveoli contain lipid vacuoles and proteinaceous droplets. Anisokaryosis, a common feature of tumors with altered Trp53 expression, is prominent.

Description

Lobular hyperplasia with atypia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29179
Tumor Name
Mammary gland • hyperplasia - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
Lobular hyperplasia with atypia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(Trp53R172H)8512Jmr Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps(Trp53R172H)8512Jmr
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown