Pathology Image Detail

Caption

Mammary gland: mammary lobules are prominent, are filled with an often inspissated proteinaceous fluid, and are lined by a prominent epithelium. Luminal cells of all alveoli contain lipid vacuoles and proteinaceous droplets. Anisokaryosis, a common feature of tumors with altered Trp53 expression, is prominent. There is also moderate interstitial lymphocytic and plasmacytic inflammation.

Description

Lobular hyperplasia with atypia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29179
Tumor Name
Mammary gland • hyperplasia - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
Lobular hyperplasia with atypia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(Trp53R172H)8512Jmr Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps(Trp53R172H)8512Jmr
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown