Pathology Image Detail

Caption

Mammary gland: the mammary parenchyma is focally effaced by a small, nodular, densely cellular neoplastic mass surrounded by a thin fibrous capsule. This neoplasm is composed of closely packed glands lined by a one cell-thick cuboidal epithelium supported by a small amount of fibrovascular stroma. The glands are dilated by a small amount of proteinaceous material. The cells are cuboidal, with indistinct cell borders and a moderate amount of strongly acidophilic cytoplasm that often lipid vacuoles and proteinaceous droplets of various sizes. The nucleus is often basal, round to oval, and slightly hypochromatic. Anisokaryosis and anisocytosis are mild. A few mitoses are present.

Description

Adenoma, glandular, secretory, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29181
Tumor Name
Mammary gland • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenoma, glandular, secretory, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(Trp53R172H)8512Jmr Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps(Trp53R172H)8512Jmr
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown