Pathology Image Detail

Caption

Glandular adenoma of the mammary gland: the neoplasm is composed of closely-packed glands lined by a one cell-thick cuboidal epithelium supported by a moderate amount of fibrovascular stroma. Most of these glands show mild to moderate ectasia and are filled by a proteinaceous fluid. Neoplastic cells have indistinct cell borders and a moderate amount of acidophilic cytoplasm that often contains numerous lipid vacuoles and proteinaceous droplets of various sizes. The nucleus is often basal, round, and hyperchromatic. Anisokaryosis and anisocytosis are moderate. Mitoses are not found in this field.

Description

Adenoma, glandular, secretory, with atypia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29183
Tumor Name
Mammary gland • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenoma, glandular, secretory, with atypia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(MtTGFA)100Lmb
Strain Types
transgenic
Strain Synonyms
MT100
MT100 FVB/n
MT-TGFα
line MT100
FVB/N-derived MT100
FVB/N (TGFα)
MT-TGFα
MT-TGF-α
TGFα
FVB/N-TgN(MtTGFA)100Lmb
FVB/N-Tg(MT-Tgfa)#Lmb
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown