Caption |
Mammary gland: neoplastic ducts are lined by a one cell-thick cuboidal epithelium. Neoplastic ducts are often distended by a proteinaceous fluid. Neoplastic cells have ill-defined cell borders and a moderate amount of a strongly amphophilic cytoplasm that often contains lipid vacuoles. The nucleus is central, round, medium-sized and normochromatic. Anisokaryosis and anisocytosis are mild. A few mitoses (arrowhead) are detected. Myoepithelial differentiation (arrows) is present. The stroma is abundant, contains numerous myofibroblasts, a small number of inflammatory cells, and loosely arranged wavy and thin collagen fibers. |