Caption |
Mammary gland: the neoplasm is composed of closely packed contoured and anastomosed one cell-thick tubules and glands supported by a scant amount of fibrovascular stroma. Neoplastic cells are cuboidal, with indistinct cell borders and a moderate amount of amphophilic cytoplasm that often contains lipid vacuoles. The nucleus is central, round, and medium-sized. Anisokaryosis and anisocytosis are mild. Tubules (*) have a "crowded" appearance and resemble intralobular ducts. The glands have morphologic features consistent with the epithelium of mammary acini. There is a mild interstitial infiltration by lymphocytes, plasma cells and macrophages. |