Pathology Image Detail

Caption

Mammary gland: there was, at the periphery of the solid mammary carcinoma, a dilated interlobular duct that was lined by a 5-10 cells-thick epithelium that often formed small secondary lumens. Myoepithelial differentiation was not identified in this duct. This lesion may represent invasion of an interlobular duct by the solid carcinoma, or may indicate in situ carcinoma in an interlobular duct adjancent to a mammary carcinoma. The formation of a relatively large number of secondary lumens, a feature that was not detected in the solid carcinoma, supports a diagnosis of in situ carcinoma.

Description

Carcinoma in situ, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29191
Tumor Name
Mammary gland • carcinoma in situ
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma in situ, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(MMTV-Erbb2)NF1Mul
Strain Types
transgenic
Strain Synonyms
FVB/N-TgN(MMTV-Erbb2)NF1Mul
MMTV/c-neu
neu
NF/+
TG.NF
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown