Pathology Image Detail

Caption

 Squamous cell carcinoma of the eyelid. Cells of the stratum spinosum of the normal epidermis stain strongly for keratin 1. Neoplastic cells stain faintly.

Description

 Eyelid, squamous cell carcinoma

Age at Necropsy

 510 days

Contributor

 Mikaelian I (J:94310)

Pathologist

 Mikaelian I (J:94310)

Method

 IHC for keratin 1
Image Probes

Type: antibody
Name
anti-keratin 1 (PRB-165P)
Target
mouse keratin 1, C-terminus
Supplier
Biolegend, formerlyCovance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 1 protein, VKTVSTYSRGTK.

Model
MMHC ID
MTB:17123
Tumor Name
Eye - Eyelid • squamous cell carcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
squamous cell carcinoma
Organ Affected
Eye - Eyelid
Frequency
observed
Reference
J:94310

Strain
Strain
BALB/cByJ-Lgi4clp
Strain Types
spontaneous mutation
General Note
Mice homozygous for a spontaneous (recessive) mutation, Lgi4clp.
Strain Synonyms
BALB/cByJ-clp/clp
BALB/cByJ-clp
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
510 days