Pathology Image Detail

Caption

Comedo mammary adenocarcinoma: the neoplasm is composed of thick trabeculae and solid areas supported by a small amount of fibrovascular stroma. Neoplastic cells occasionally form inconspicuous lumens (arrowhead). Neoplastic cells are medium-sized, polygonal, with indistinct cell borders and a moderate amount of strongly amphophilic cytoplasm. The nucleus is central and oval.

Description

Adenocarcinoma, circumscribed, solid, comedo, glandular, mammary gland

Age at Necropsy

120 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29199
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, circumscribed, solid, comedo, glandular, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
B6;SJL-Tg(Mt1-Tgfa)147Bri Tg(WapMyc)212Bri
Strain Types
transgenic
General Note
Double transgenic mice. The genetic background of these mice is a mixture of C57BL/6 and SJL.
Strain Synonyms
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
120 days