Caption |
In situ mammary carcinoma: there is prominent proliferation of cells in a mammary alveolus. Thin fibrovascular projections subdivide the alveolus. Proliferating cells are large, with indistinct cell borders and a moderate amount of pale acidophilic cytoplasm. The nucleus is central, oval, medium-sized and slightly hypochromatic. Anisokaryosis and anisocytosis are mild. There is no evidence of invasion. There is mild to moderate interstitial fibrosis and lymphocytic and plasmacytic inflammation. Myoepithelial differentiation is not detected in this portion of the lesion. |