Caption |
Mammary gland: hypercellularity of mammary lobules is the result of proliferation of luminal cells of mammary alveoli and intralobular ducts. These cells pile-up and occlude the lumen of some alveoli. The cells populating this lobule are very heterogeneous. About 30% of these cells have primitive features: they are oval, with a pale acidophilic cytoplasm and a medium-sized slightly hypochromatic nucleus. The other cells are more differentiated and have a cuboidal to low columnar shape, a more strongly acidophilic cytoplasm and a normochromatic nucleus. There is no evidence of atypia but a few mitoses (arrowheads) are detected. There is no evidence of local invasion. There is mild interstitial fibrosis and lymphocytic and plasmacytic inflammation. |