Pathology Image Detail

Caption

Mammary gland: the neoplasm is composed of closely-packed branching glands with an inconspicuous lumen. These glands are lined by a one cell-thick epithelium and are supported by a small amount of fibrovascular stroma. Neoplastic cells are low columnar, with indistinct cell borders and a moderate amount of acidophilic cytoplasm. The nucleus is basal, often oriented in the long axis of the cell, medium-sized,normochromatic, with a finely stippled chromatin and 1-2 small basophilic nucleoli. Anisokaryosis and anisocytosis are mild. A few mitoses are present.

Description

Adenocarcinoma, glandular, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29206
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, glandular, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
B6;C-Tg(MMTV-RET)127Ina
Strain Types
transgenic
General Note
The genetic background of these mice was a mixture of C57BL/6 and BALB/c.
Strain Synonyms
(C57BL6xBalb/c)-Tg(MMTVRet)1Ina
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown