Pathology Image Detail

Caption

Solid mammary adenocarcinoma: there are three morphologic types of neoplastic cells. First, at the periphery of the neoplasms, there are small clusters of large cells with a pale cytoplasm and an hypochromatic nucleus. Second, around the areas of liquefactive necrosis, neoplastic cells are small, with a condensed nucleus and a small amount of cytoplasm. Third, acounting for the majority of neoplastic cells, there is a population of medium-sized polygonal cells with indistinct cell borders, a moderate amount of strongly acidophilic cytoplasm, and a medium-sized central normochromatic nucleolus.

Description

Adenocarcinoma, solid, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29231
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(MMTVneu)202Mul Tg(Trp53R172H)8512Jmr
Strain Types
transgenic
Strain Synonyms
FVB/N-TgN(MMTVneu)202Mul TgN(Trp53R172H)8512Jmr
bitransgenic
line 8512 WAP-p53-172H line N# 202 MMTV-neu
WAP-p53-172H MMTV-neu
p53-172H/neu bitransgenic
FVB/N-Tg(MMTVneu)202Mul Tg(Trp53R172H)8512Jmr
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown