Pathology Image Detail

Caption

Solid mammary adenocarcinoma: the neoplasm is composed of two types of neoplastic cells. First, at the periphery of the neoplasm, there are small ill-defined clusters of large neoplastic cells with a pale cytoplasm and an hypochromatic nucleus. Second, accounting for most of the neoplasm, there are medium-sized polygonal cells with indistinct cell borders and a moderate amount of acidophilic cytoplasm. Anisokaryosis and anisocytosis are mild. Neoplastic cells occasionally form inconspicuous secondary lumens (arrowhead).

Description

Adenocarcinoma, solid, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29232
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(MMTVneu)202Mul Tg(Trp53R172H)8512Jmr
Strain Types
transgenic
Strain Synonyms
FVB/N-TgN(MMTVneu)202Mul TgN(Trp53R172H)8512Jmr
bitransgenic
line 8512 WAP-p53-172H line N# 202 MMTV-neu
WAP-p53-172H MMTV-neu
p53-172H/neu bitransgenic
FVB/N-Tg(MMTVneu)202Mul Tg(Trp53R172H)8512Jmr
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown