Caption |
Lung: a small metastasis of a mammary tumor is present. This metastasis is predominantly composed of cell located within the lumen of a small artery (neoplastic embolus), but also of neoplastic cells that have escaped the lumen of the artery to invade the pulmonary interstitial (true metastasis). The endothelium of the artery (arrowhead) is still discernible. Neoplastic cells are polygonal, with ill-defined cell borders and a moderate amount of homogeneous acidophilic cytoplasm. Anisocytosis and anisokaryosis are mild. Nearby alveoli contain macrophages the cytoplasm of which is distended by acidophilic crystals (acidophilic crystals pneumonia). |
