Pathology Image Detail

Caption

Mammary adenoma: this photomicrograph of the periphery of the neoplasm illustrates the radiating glandular pattern with gradual transition into cords and trabeculae. Neoplastic cells are medium-sized, polygonal to cuboidal, with indistinct cell borders and a moderate amount of homogeneously eosinophilic cytoplasm. The nucleus is basal, round, and normochromatic. Anisocytosis and anisokaryosis overal are mild, although a few cells have a very large nucleus (arrowhead). There is prominent hyperplasia and atypia in the nearby mammary parenchyma.

Description

Adenoma, glandular, with prominent atypia, and diffuse hyperplasia with atypia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29238
Tumor Name
Mammary gland • adenoma
Treatment Type
Chemical/Drug
Agents
[Agent] - Agent._Agent_key = [7] - Agent._AgentType_key = [3] - Agent.name = [7,12-dimethylbenz[a]anthracene (DMBA)] - Agent.description = [null] - Agent.create_user = [MTB] - Agent.create_date = [2005-01-05 13:31:30.0] - Agent.update_user = [dmk] - Agent.update_date = [2007-06-26 11:16:55.0]
[Agent] - Agent._Agent_key = [2] - Agent._AgentType_key = [5] - Agent.name = [pituitary isograft] - Agent.description = [null] - Agent.create_user = [MTB] - Agent.create_date = [2005-01-05 13:31:30.0] - Agent.update_user = [MTB] - Agent.update_date = [2005-01-05 13:31:30.0]
Tumor Synonyms
Adenoma, glandular, with prominent atypia, and diffuse hyperplasia with atypia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(Trp53R172H)8512Jmr
Strain Types
transgenic
Strain Synonyms
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown