Pathology Image Detail

Caption

Mammary gland: the mammary gland is expanded by an invasive neoplasm characterized by the formation of large solid nests of neoplastic cells with various degrees of central necrosis and cavitation. Neoplastic cells are medium-sized, with indistinct cell borders and a moderate amount of amphophilic to basophilic cytoplasm. The nucleus is central, oval, medium-size, and slightly hypochromatic. Anisokaryosis and anisocytosis are mild. Mitoses are very numerous. There is mild fibrosis and pleocellular inflammation at the periphery of neoplastic nests.

Description

Adenocarcinoma, solid, comedo, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29242
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, comedo, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
NMRI-Tg(Wap-Tag)8Gmn
Strain Types
transgenic
Strain Synonyms
NMRI-Tg(Wap-SV40)1Gmn
WAP-SVT/t, line 8
WAP-SVT/t
WAP-SVT/t (strain NMRI)
WAP-SV-T
WAP-SV-T line 8
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown