Caption |
Mammary gland: the mammary gland is replaced by a densely cellular neoplasm composed of closely-packed glands and branching ducts lined by a 1-2 cells-thick cuboidal epithelium and separated by a small amount of fibrovascular stroma. Some ducts are moderately ectatic and filled by a strongly acidophilic amorphous material and desquamated neoplastic cells. Neoplastic cells are cuboidal, with indistinct cell borders and a moderate amount of amphophilic cytoplasm. The nucleus is central, round to oval, occasionally oriented in the long axis of the cell, medium-size, hyperchromatic, with a coarsely clumped chromatin and 1-4 small basophilic nucleoli. Anisokaryosis and anisocytosis are mild. Mitoses are numerous. |