Pathology Image Detail

Caption

Trabecular mammary adenocarcinoma: neoplastic cells form interconnected trabeculae that are 2-3 cells thick and that are separated by a moderate amount of fibrovascular stroma with a prominent pleocellular infiltrate. Neoplastic cells show prominent nuclear palissading at the periphery of the trabeculae. Luminal spaces are not detected. Neoplastic cells are cuboidal to low columnar, with indistinct cell borders and a small to moderate amount of amphophilic cytoplasm. The nucleus is basal, oval and medium-size. Numerous areas of necrosis are present.

Description

Adenocarcinoma, trabecular, solid, with prominent fibrosis and coagulation necrosis, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29268
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, trabecular, solid, with prominent fibrosis and coagulation necrosis, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
NMRI-Tg(Wap-Tag)8Gmn
Strain Types
transgenic
Strain Synonyms
NMRI-Tg(Wap-SV40)1Gmn
WAP-SVT/t, line 8
WAP-SVT/t
WAP-SVT/t (strain NMRI)
WAP-SV-T
WAP-SV-T line 8
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown