Pathology Image Detail

Caption

Solid mammary carcinoma: neoplastic lobules are composed of closely-packed cells and often show central areas of liquefactive necrosis (comedo pattern). There is prominent nuclear palissading at the periphery of neoplastic lobules. Neoplastic cells are medium-size, polygonal, with indistinct cell borders and a small amount of acidophilic cytoplasm. The nucleus is central, oval, normochromatic, and with a coarsely clumped chromatin. Anisokaryosis and anisocytosis are mild. There are numerous mitoses.

Description

Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29269
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
NMRI-Tg(Wap-Tag)8Gmn
Strain Types
transgenic
Strain Synonyms
NMRI-Tg(Wap-SV40)1Gmn
WAP-SVT/t, line 8
WAP-SVT/t
WAP-SVT/t (strain NMRI)
WAP-SV-T
WAP-SV-T line 8
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown