Caption |
Solid mammary carcinoma: neoplastic lobules are composed of closely-packed cells and often show central areas of liquefactive necrosis (comedo pattern). There is prominent nuclear palissading at the periphery of neoplastic lobules. Neoplastic cells are medium-size, polygonal, with indistinct cell borders and a small amount of acidophilic cytoplasm. The nucleus is central, oval, normochromatic, and with a coarsely clumped chromatin. Anisokaryosis and anisocytosis are mild. There are numerous mitoses. |