Caption |
Lung: the photomicrograph represents a pulmonary metastasis of a mammary neoplasm. It is composed of small coalescing nests separated by a scant amount of fibrovascular stroma. Neoplastic cells are cuboidal, polygonal or oat-shaped, with ill-defined cell borders and a small amount of amphophilic cytoplasm. The nucleus is central, oval, normochromatic, with a finely stippled chromatin and 1-5 small basophilic nucleoli. Anisokaryosis and anisocytosis are mild. Numerous neoplastic cells undergo single cell necrosis, especially at the center of neoplastic nests. |