Pathology Image Detail

Caption

Mammary gland: the overall architecture of the mammary gland is maintained. Most interlobular ducts and a few intralobular ducts are moderately distended by a proteinaceous material that contains a few desquamated epithelial clels and macrophages. All intralobular ducts and acini are hypercellular and lined by a 1-3 cells-thick epithelium. In this field, epithelial cells often contain cytoplasmic lipid vacuoles. Mitoses are numerous.

Description

Carcinoma in situ and atypical lobular hyperplasia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29275
Tumor Name
Mammary gland • hyperplasia - atypical - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
atypical lobular hyperplasia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
STOCK Tg(Wap-BCL2)#Jag Tg(Wap-Tag)8Gmn
Strain Types
transgenic
General Note
This STOCK genetic background was a mixture of strains including at least NMRI, C57BL/6, and DBA/2.
Strain Synonyms
NMRI-Tg(WapSV40)(WapBcl2)#?
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown