Pathology Image Detail

Caption

Mammary gland: this photomicrograph illustrates acini where epithelial cells pile-up disorderly up to 3-4 cells-thick. Other changes consist in lipid vacuoles in the cytoplasm of a few epithelial cells, desquamated epithelial cells and macrophages intermingled with a proteinaceous material in the lumen of all acini and intralobular ducts, an elevated mitotic rate, and the presence of numerous epithelial cells undergoing single cell necrosis.

Description

Carcinoma in situ and atypical lobular hyperplasia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29274
Tumor Name
Mammary gland • carcinoma in situ
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma in situ, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
STOCK Tg(Wap-BCL2)#Jag Tg(Wap-Tag)8Gmn
Strain Types
transgenic
General Note
This STOCK genetic background was a mixture of strains including at least NMRI, C57BL/6, and DBA/2.
Strain Synonyms
NMRI-Tg(WapSV40)(WapBcl2)#?
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown