Pathology Image Detail

Caption

Mammary gland: the architecture of the mammary gland is maintained. All the acini and intralobular ducts of a mammary lobule are filled with and slightly distended by solid masses of epithelial cells. There is moderate interstitial fibrosis and pleocellular inflammation. Neoplastic cells are polygonal, with indistinct cell borders and a moderate amount of amphophilic cytoplasm. Numerous neoplastic cells undergo single cell necrosis.

Description

Ductal carcinoma in situ, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29277
Tumor Name
Mammary gland • carcinoma in situ - ductal
Treatment Type
None (spontaneous)
Tumor Synonyms
Ductal carcinoma in situ, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
STOCK Tg(Wap-BCL2)#Jag Tg(Wap-Tag)8Gmn
Strain Types
transgenic
General Note
This STOCK genetic background was a mixture of strains including at least NMRI, C57BL/6, and DBA/2.
Strain Synonyms
NMRI-Tg(WapSV40)(WapBcl2)#?
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown