Caption |
Ductal carcinoma in situ: there is keratinization of individual neoplastic cells (arrowheads). These cells have angular contours, a more acidophilic cytoplasm, and a larger and more hypochromatic nucleus with a larger nucleolus than nearby neoplastic cells. The other neoplastic cells are polygonal, with indistinct cell borders, a small amount of dark amphophilic cytoplasm, and a medium-size, oval, hyperchromatic nucleus with a punctate chromatin. Anisokaryosis and anisocytosis are mild. Mitosis and neoplastic cells undergoing single cell necrosis are numerous. |
